Cleveland Wins $160M Advanced Manufacturing Grant
Northeast Ohio beat out more than 300 regions to earn the funding, which could propel Northeast Ohio and the entire state as a national center for manufacturing innovation, technology and jobs.
by Ken Prendergast, NEOTrans | Jul. 14, 2026 | 5:49 PM
Courtesy Harrison Whittaker, NEOtrans
Hundreds of regions competed for a large, prestigious grant from the U.S. National Science Foundation to boost advanced manufacturing. But it was a 70-member coalition from Northeast Ohio that came out on top today.
The partners in the coalition, led by Case Western Reserve University, included private industry, civic and philanthropic organizations, higher education, and state and local government were designated an NSF Engine.
It could bring up to $160 million in federal investment to propel Northeast Ohio and the entire state as a national center for manufacturing innovation, technology and jobs.
The coalition, the NSF NEO-SMART Engine in Northeast Ohio was rewarded for its Regional Innovation Engines program. NEO-SMART stands for Northeast Ohio Strengthening Manufacturing for American Resilience through Technology.
Funding will be awarded over 10 years, with $7.5 million in each of the first two years, $15 million annually for the following three years and $20 million for each of the final five years as milestones are met.
NEO-SMART partners also have already committed another $120 million for the first two years, with aspirations to attract a total of more than $500 million in public, private and philanthropic investment as the work progresses.
Last September, NEO-SMART members were informed they were among 15 finalists nationwide to make the final round of competition. Two months before, NEO-SMART was among 29 semi-finalists, emerging from a field of 300 competitors.
“This is great news for Northeast Ohio and for the entire state of Ohio,” said Ohio Gov. Mike DeWine in a written statement. “When federal dollars come to our state to strengthen manufacturing and build up our workforce, every Ohioan benefits—and I am grateful for the extensive partnership effort that made this award possible.”
“Greater Cleveland Partnership (GCP) and our companies are ready to invest and move,” said Baju Shah, president and CEO of the CEP and NEO-SMART governing board member.
“We will work hand-in-hand with the institutions, public partners, and community to ensure every dollar of this historic investment is deployed to drive innovation, jobs and regional growth,” he added. “Greater Cleveland does not just want to participate in the next era of American manufacturing — we intend to create and lead it.”
Plans to grow jobs, spur innovation
At the core of NEO-SMART’s vision is capitalizing on — and elevating — Northeast Ohio’s strengths in metals, polymers and chemicals and coatings to become a national hub for what is known as advanced manufacturing.
The effort will integrate innovative technologies such as artificial intelligence (AI) for materials design, automation and robotics to improve production methods and create new products. More specifically, NEO-SMART’s goals are to:
Create or retain 20,000 jobs across the 18-county region through a strategy to re-industrialize Northeast Ohio. That includes training 12,000 workers over 10 years for “in-demand,” meaningful jobs through new curriculum in materials and manufacturing at the region’s universities and colleges.
Reinforce domestic supply chains in sectors such as automotive, aerospace, defense and medical devices.
Propel innovation by advancing key technologies, such as AI/machine learning in manufacturing, and fostering entrepreneurship. The partners plan to increase corporate research and development (R&D) by 50 percent and support 150 R&D projects over the next 10 years.
Bolster industry-academic research partnerships that accelerate “lab-to-market” innovation — a strategy to support 1,000 ventures and provide more than 250 “seed” investments for start-up companies.
Multi-Sector Regional Collaboration
Like many Midwest industrial centers that once drove American manufacturing, Northeast Ohio faced significant challenges and decline due to globalization, technological shifts and often disjointed strategies for regional economic growth.
Nick Barendt, NEO-SMART’s CEO, explained successful place-based innovation and economic growth is rooted in the alignment of partners from industry, higher education, government, nonprofits, economic development and philanthropy that co-create ecosystems to solve the research, translation and workforce challenges.
Coalition buy-in spans partners regionwide, from Greater Cleveland to Akron and Canton, and from Lorain County to Youngstown. Each sector will play a critical role in the vision’s success.
“The manufacturing challenges of the next decade will be solved by academic researchers, industry partners and factory floor teams who work in collaboration to turn scientific insight into commercial reality,” said CWRU President Eric Kaler. CWRU’s new $300 million Interdisciplinary Science & Engineering Building will be a key player.
“We are tremendously grateful for the extraordinary support and advocacy we received from federal, state and local elected officials that led to this funding opportunity,” he continued. “Together, we will advance the region’s growth and prosperity.”
The NEO-SMART team recognizes DeWine and JobsOhio President and CEO J.P. Nauseef for supporting a robust state co-investment in the grant proposal. The NSF Engines program also is made possible with support from Ohio’s congressional delegation.
“Northeast Ohio’s competitive advantages in advanced manufacturing and next-generation technologies make the NSF Engine award a natural fit and will enhance the region’s existing strengths in these areas,” Nauseef said.
About NSF Regional Innovation Engines Program
The U.S. National Science Foundation established its NSF Engines program in 2022 to accelerate the development and deployment of U.S.-produced technology in sectors critical to national security and American competitiveness.
In only its second round of funding awards since 2022, the NSF chose NEO-SMART from over 300 concepts submitted for rigorous, multi-stage evaluation. NEO-SMART is one of 12 Engines selected nationwide in this round of funding, and the only one in Ohio.
Teams that demonstrate progress on well-defined milestones will have the potential to receive up to $160 million each from NSF over the next decade as they seek to build an internationally competitive technology and innovation cluster in their region.
“NSF Engines investments in critical technologies and future industries will transform America’s innovation infrastructure for decades to come,” said Brian Stone, performing the duties of the NSF director.
“The NSF NEO-SMART Engine will expand domestic manufacturing capacity, grow the region’s skilled workforce, and create economic opportunities, fostering a more resilient U.S. industrial base and supply chain,” he added.
For more updates about Cleveland, sign up for our Cleveland Magazine Daily newsletter, delivered to your inbox six times a week.
Cleveland Magazine is also available in print, featuring immersive stories, helpful guides and beautiful photography and design.
Ken Prendergast, NEOTrans
Ken Prendergast is a local professional journalist who loves and cares about Cleveland, its history and its development. He has worked as a journalist for more than three decades for publications such as NEOtrans, Sun Newspapers, Ohio Passenger Rail News, Passenger Transport, and others. He also provided consulting services to transportation agencies, real estate firms, port authorities and nonprofit organizations. He runs NEOtrans Blog covers the Greater Cleveland region’s economic, development, real estate, construction and transportation news since 2011. His content is published on Cleveland Magazine as part of an exclusive sharing agreement.
